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Neutral Antibodies to the TSH Receptor Are Present in Graves’ Disease and Regulate Selective Signaling Cascades
TSH receptor (TSHR) antibodies (Abs) may be stimulating, blocking, or neutral in their functional influences and are found in patients with autoimmune thyroid disease, especially Graves’ disease (GD). Stimulators are known to activate the thyroid epithelial cells via both Gs- and Gq-coupled signalin...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Endocrine Society
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2954721/ https://ncbi.nlm.nih.gov/pubmed/20844004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0424 |
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