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Neutral Antibodies to the TSH Receptor Are Present in Graves’ Disease and Regulate Selective Signaling Cascades

TSH receptor (TSHR) antibodies (Abs) may be stimulating, blocking, or neutral in their functional influences and are found in patients with autoimmune thyroid disease, especially Graves’ disease (GD). Stimulators are known to activate the thyroid epithelial cells via both Gs- and Gq-coupled signalin...

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Detaylı Bibliyografya
Asıl Yazarlar: Morshed, Syed A., Ando, Takao, Latif, Rauf, Davies, Terry F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Endocrine Society 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954721/
https://ncbi.nlm.nih.gov/pubmed/20844004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0424
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