Acidic polyamino acids inhibit human eosinophil granule major basic protein toxicity. Evidence of a functional role for ProMBP.

Eosinophil granule major basic protein (MBP), a potent toxin for helminths and mammalian cells in vitro, is a single polypeptide chain rich in arginine. MBP has been localized on damaged helminths and tissues in hypersensitivity diseases including bronchial asthma. The MBP cDNA indicates that MBP is...

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Detalhes bibliográficos
Main Authors: Barker, R L, Gundel, R H, Gleich, G J, Checkel, J L, Loegering, D A, Pease, L R, Hamann, K J
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC295464/
https://ncbi.nlm.nih.gov/pubmed/1715886
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