BAG3 directly associates with guanine nucleotide exchange factor of Rap1, PDZGEF2, and regulates cell adhesion

BAG3, a member of the Hsc70 binding co-chaperone BAG-family proteins, has critical roles in regulating actin organization, cell adhesion, cell motility and tumor metastasis. The PDZ domain containing Guanine Nucleotide Exchange Factor 2 (PDZGEF2) was cloned as a BAG3 interacting protein. PDZGEF2 ind...

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Main Authors: Iwasaki, Masahiro, Tanaka, Ryoichi, Hishiya, Akinori, Homma, Sachiko, Reed, John C., Takayama, Shinichi
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954587/
https://ncbi.nlm.nih.gov/pubmed/20800573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.08.092
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