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BAG3 Deficiency Results in Fulminant Myopathy and Early Lethality

Bcl-2-associated athanogene 3 (BAG3) is a member of a conserved family of cyto-protective proteins that bind to and regulate Hsp70 family molecular chaperones. Here, we show that BAG3 is prominently expressed in striated muscle and colocalizes with Z-disks. Mice with homozygous disruption of the bag...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Homma, Sachiko, Iwasaki, Masahiro, Shelton, G. Diane, Engvall, Eva, Reed, John C., Takayama, Shinichi
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Investigative Pathology 2006
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698816/
https://ncbi.nlm.nih.gov/pubmed/16936253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060250
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