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Folding Domains within the Ricin Toxin A Subunit as Targets of Protective Antibodies

Efforts to develop an effective vaccine against ricin are focused on the engineering of attenuated and stable recombinant forms of the toxin’s enzymatic A subunit (RTA). While several candidate antigens are in development, vaccine design and efficacy studies are being undertaken in the absence of a...

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Bibliographic Details
Main Authors: O’Hara, Joanne M., Neal, Lori M., McCarthy, Elizabeth A., Kasten-Jolly, Jane A., Brey, Robert N., Mantis, Nicholas J.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954487/
https://ncbi.nlm.nih.gov/pubmed/20727394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.08.020
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