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Trivalent Arsenic Inhibits the Functions of Chaperonin Complex

The exact molecular mechanisms by which the environmental pollutant arsenic works in biological systems are not completely understood. Using an unbiased chemogenomics approach in Saccharomyces cerevisiae, we found that mutants of the chaperonin complex TRiC and the functionally related prefoldin com...

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Detalles Bibliográficos
Main Authors: Pan, Xuewen, Reissman, Stefanie, Douglas, Nick R., Huang, Zhiwei, Yuan, Daniel S., Wang, Xiaoling, McCaffery, J. Michael, Frydman, Judith, Boeke, Jef D.
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954479/
https://ncbi.nlm.nih.gov/pubmed/20660648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.117655
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