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Trivalent Arsenic Inhibits the Functions of Chaperonin Complex

The exact molecular mechanisms by which the environmental pollutant arsenic works in biological systems are not completely understood. Using an unbiased chemogenomics approach in Saccharomyces cerevisiae, we found that mutants of the chaperonin complex TRiC and the functionally related prefoldin com...

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Detalhes bibliográficos
Main Authors: Pan, Xuewen, Reissman, Stefanie, Douglas, Nick R., Huang, Zhiwei, Yuan, Daniel S., Wang, Xiaoling, McCaffery, J. Michael, Frydman, Judith, Boeke, Jef D.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954479/
https://ncbi.nlm.nih.gov/pubmed/20660648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.117655
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