Mutations in human cytomegalovirus UL97 gene confer clinical resistance to ganciclovir and can be detected directly in patient plasma.

Specific mutations in the UL97 region of human cytomegalovirus (HCMV) have been found to confer resistance to laboratory-adapted strains subjected to ganciclovir selection. In this study, mutations in the UL97 region of HCMV isolates obtained from patients receiving ganciclovir therapy were examined...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Wolf, D G, Smith, I L, Lee, D J, Freeman, W R, Flores-Aguilar, M, Spector, S A
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1995
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295420/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7814623/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117648
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!