Phosphorylation of p27(Kip1) at Thr187 by Cyclin-dependent Kinase 5 Modulates Neural Stem Cell Differentiation

Cyclin-dependent kinase 5 (Cdk5) plays a key role in the development of the mammalian nervous system; it phosphorylates a number of targeted proteins involved in neuronal migration during development to synaptic activity in the mature nervous system. Its role in the initial stages of neuronal commit...

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Hlavní autoři: Zheng, Ya-Li, Li, Bing-Sheng, Rudrabhatla, Parvathi, Shukla, Varsha, Amin, Niranjana D., Maric, Dragan, Kesavapany, Sashi, Kanungo, Jyotshnabala, Pareek, Tej K., Takahashi, Satoru, Grant, Philip, Kulkarni, Ashok B., Pant, Harish C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954124/
https://ncbi.nlm.nih.gov/pubmed/20810788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-01-0054
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