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Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression

Carcinogenesis is a complex, multistep, multipath process often described as “somatic evolution.” Conventional models of cancer progression are typically based on the genetic and epigenetic changes observed in malignant and premalignant tumors. We have explored an alternative approach that emphasize...

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Autori principali: Fang, Jennifer S., Gillies, Robert D., Gatenby, Robert A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953714/
https://ncbi.nlm.nih.gov/pubmed/18455429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2008.03.011
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