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Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression

Carcinogenesis is a complex, multistep, multipath process often described as “somatic evolution.” Conventional models of cancer progression are typically based on the genetic and epigenetic changes observed in malignant and premalignant tumors. We have explored an alternative approach that emphasize...

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Detalhes bibliográficos
Main Authors: Fang, Jennifer S., Gillies, Robert D., Gatenby, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953714/
https://ncbi.nlm.nih.gov/pubmed/18455429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2008.03.011
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