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Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression

Carcinogenesis is a complex, multistep, multipath process often described as “somatic evolution.” Conventional models of cancer progression are typically based on the genetic and epigenetic changes observed in malignant and premalignant tumors. We have explored an alternative approach that emphasize...

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Bibliografiske detaljer
Main Authors: Fang, Jennifer S., Gillies, Robert D., Gatenby, Robert A.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953714/
https://ncbi.nlm.nih.gov/pubmed/18455429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2008.03.011
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