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Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression
Carcinogenesis is a complex, multistep, multipath process often described as “somatic evolution.” Conventional models of cancer progression are typically based on the genetic and epigenetic changes observed in malignant and premalignant tumors. We have explored an alternative approach that emphasize...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2953714/ https://ncbi.nlm.nih.gov/pubmed/18455429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2008.03.011 |
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