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Evolutionary Dynamics Unifies Carcinogenesis and Cancer Therapy

All malignant cancers, whether inherited or sporadic, are fundamentally governed by Darwinian dynamics. The process of carcinogenesis requires genetic instability and highly selective local microenvironments, the combination of which promotes somatic evolution. These microenvironmental forces, speci...

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Detalhes bibliográficos
Main Authors: Gillies, Robert J., Verduzco, Daniel, Gatenby, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122506/
https://ncbi.nlm.nih.gov/pubmed/22695393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3298
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