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Evolutionary Dynamics Unifies Carcinogenesis and Cancer Therapy
All malignant cancers, whether inherited or sporadic, are fundamentally governed by Darwinian dynamics. The process of carcinogenesis requires genetic instability and highly selective local microenvironments, the combination of which promotes somatic evolution. These microenvironmental forces, speci...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4122506/ https://ncbi.nlm.nih.gov/pubmed/22695393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3298 |
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