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Evolutionary Dynamics Unifies Carcinogenesis and Cancer Therapy

All malignant cancers, whether inherited or sporadic, are fundamentally governed by Darwinian dynamics. The process of carcinogenesis requires genetic instability and highly selective local microenvironments, the combination of which promotes somatic evolution. These microenvironmental forces, speci...

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Autors principals: Gillies, Robert J., Verduzco, Daniel, Gatenby, Robert A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122506/
https://ncbi.nlm.nih.gov/pubmed/22695393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3298
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