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Use of Recombinant Cell Permeable Small Peptides to Modulate Glucocorticoid Sensitivity of Acute Lymphoblastic Leukemia Cells
Glucocorticoid (GC) hormones induce apoptosis in T-cell and pre-B-cell acute lymphoblastic leukemia (ALL) cells. Steroid-mediated apoptosis requires a threshold level of the glucocorticoid receptor (GR) protein, and increasing the intracellular GR levels in ALL cells would augment their hormone-sens...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2953583/ https://ncbi.nlm.nih.gov/pubmed/20831260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1007723 |
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