The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy

Autophagy is an evolutionary conserved catabolic process involved in several physiological and pathological processes such as cancer and neurodegeneration. Autophagy initiation signaling requires both the ULK1 kinase and the BECLIN 1–VPS34 core complex to generate autophagosomes, double-membraned ve...

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Main Authors: Di Bartolomeo, Sabrina, Corazzari, Marco, Nazio, Francesca, Oliverio, Serafina, Lisi, Gaia, Antonioli, Manuela, Pagliarini, Vittoria, Matteoni, Silvia, Fuoco, Claudia, Giunta, Luigi, D'Amelio, Marcello, Nardacci, Roberta, Romagnoli, Alessandra, Piacentini, Mauro, Cecconi, Francesco, Fimia, Gian Maria
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2010
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953445/
https://ncbi.nlm.nih.gov/pubmed/20921139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201002100
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