The Carboxy-Terminal Segment of the Human Cytomegalovirus DNA Polymerase Accessory Subunit UL44 Is Crucial for Viral Replication

The amino-terminal 290 residues of UL44, the presumed processivity factor of human cytomegalovirus DNA polymerase, possess all of the established biochemical activities of the full-length protein, while the carboxy-terminal 143 residues contain a nuclear localization signal (NLS). We found that alth...

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Autores principales: Silva, Laurie A., Loregian, Arianna, Pari, Gregory S., Strang, Blair L., Coen, Donald M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953201/
https://ncbi.nlm.nih.gov/pubmed/20739543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01033-10
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