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Specific Residues in the Connector Loop of the Human Cytomegalovirus DNA Polymerase Accessory Protein UL44 Are Crucial for Interaction with the UL54 Catalytic Subunit

The human cytomegalovirus DNA polymerase includes an accessory protein, UL44, which has been proposed to act as a processivity factor for the catalytic subunit, UL54. How UL44 interacts with UL54 has not yet been elucidated. The crystal structure of UL44 revealed the presence of a connector loop ana...

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Detalhes bibliográficos
Main Authors: Loregian, Arianna, Appleton, Brent A., Hogle, James M., Coen, Donald M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC506919/
https://ncbi.nlm.nih.gov/pubmed/15308704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.17.9084-9092.2004
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