CD8(+) T Cell Recognition of Cryptic Epitopes Is a Ubiquitous Feature of AIDS Virus Infection

Vaccines designed to elicit AIDS virus-specific CD8(+) T cells should engender broad responses. Emerging data indicate that alternate reading frames (ARFs) of both human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) encode CD8(+) T cell epitopes, termed cryptic epitopes. Here,...

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Bibliographic Details
Main Authors: Maness, Nicholas J., Walsh, Andrew D., Piaskowski, Shari M., Furlott, Jessica, Kolar, Holly L., Bean, Alexander T., Wilson, Nancy A., Watkins, David I.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Cellular Response to Infection
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953171/
https://ncbi.nlm.nih.gov/pubmed/20739530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01419-10
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