AIDS virus–specific CD8(+) T lymphocytes against an immunodominant cryptic epitope select for viral escape

Cryptic major histocompatibility complex class I epitopes have been detected in several pathogens, but their importance in the immune response to AIDS viruses remains unknown. Here, we show that Mamu-B*17 (+) simian immunodeficiency virus (SIV)mac239-infected rhesus macaques that spontaneously contr...

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Detalhes bibliográficos
Main Authors: Maness, Nicholas J., Valentine, Laura E., May, Gemma E., Reed, Jason, Piaskowski, Shari M., Soma, Taeko, Furlott, Jessica, Rakasz, Eva G., Friedrich, Thomas C., Price, David A., Gostick, Emma, Hughes, Austin L., Sidney, John, Sette, Alessandro, Wilson, Nancy A., Watkins, David I.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Brief Definitive Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118485/
https://ncbi.nlm.nih.gov/pubmed/17954573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071261
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