Robust, Vaccine-Induced CD8(+) T Lymphocyte Response against an Out-of-Frame Epitope

Rational vaccines designed to engender T cell responses require intimate knowledge of how epitopes are generated and presented. Recently, we vaccinated 8 Mamu-A*02(+) rhesus macaques with every SIV protein except Envelope (Env). Surprisingly, one of the strongest T cell responses engendered was agai...

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Detalhes bibliográficos
Main Authors: Maness, Nicholas J., Wilson, Nancy A., Reed, Jason S., Piaskowski, Shari M., Sacha, Jonah B., Walsh, Andrew D., Thoryk, Elizabeth, Heidecker, Gwendolyn J., Citron, Michael P., Liang, Xiaoping, Bett, Andrew J., Casimiro, Danilo R., Watkins, David I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881682/
https://ncbi.nlm.nih.gov/pubmed/19949108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903118
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