The β/Gcd7 Subunit of Eukaryotic Translation Initiation Factor 2B (eIF2B), a Guanine Nucleotide Exchange Factor, Is Crucial for Binding eIF2 In Vivo

Eukaryotic translation initiation factor 2B (eIF2B) is the guanine nucleotide exchange factor (GEF) for eukaryotic translation initiation factor 2, which stimulates formation of the eIF2-GTP-Met-tRNA (i)(Met) ternary complex (TC) in a manner inhibited by phosphorylated eIF2 [eIF2(αP)]. While eIF2B c...

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Detalhes bibliográficos
Main Authors: Dev, Kamal, Qiu, Hongfang, Dong, Jinsheng, Zhang, Fan, Barthlme, Dominik, Hinnebusch, Alan G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953064/
https://ncbi.nlm.nih.gov/pubmed/20805354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00265-10
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