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Insulin Regulates Adipocyte Lipolysis via an Akt-Independent Signaling Pathway
After a meal, insulin suppresses lipolysis through the activation of its downstream kinase, Akt, resulting in the inhibition of protein kinase A (PKA), the main positive effector of lipolysis. During insulin resistance, this process is ineffective, leading to a characteristic dyslipidemia and the wo...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2953052/ https://ncbi.nlm.nih.gov/pubmed/20733001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00797-10 |
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