Insulin Regulates Adipocyte Lipolysis via an Akt-Independent Signaling Pathway

After a meal, insulin suppresses lipolysis through the activation of its downstream kinase, Akt, resulting in the inhibition of protein kinase A (PKA), the main positive effector of lipolysis. During insulin resistance, this process is ineffective, leading to a characteristic dyslipidemia and the wo...

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Bibliografiske detaljer
Main Authors: Choi, Sarah M., Tucker, David F., Gross, Danielle N., Easton, Rachael M., DiPilato, Lisa M., Dean, Abigail S., Monks, Bob R., Birnbaum, Morris J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953052/
https://ncbi.nlm.nih.gov/pubmed/20733001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00797-10
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