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Akt2 is required for hepatic lipid accumulation in models of insulin resistance
Insulin drives the global anabolic response to nutrient ingestion, regulating both carbohydrate and lipid metabolism. Previous studies have demonstrated that Akt2/protein kinase B is critical to insulin’s control of glucose metabolism, but its role in lipid metabolism has remained controversial. Her...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796129/ https://ncbi.nlm.nih.gov/pubmed/19883618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.10.004 |
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