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Akt2 is required for hepatic lipid accumulation in models of insulin resistance

Insulin drives the global anabolic response to nutrient ingestion, regulating both carbohydrate and lipid metabolism. Previous studies have demonstrated that Akt2/protein kinase B is critical to insulin’s control of glucose metabolism, but its role in lipid metabolism has remained controversial. Her...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Leavens, Karla F., Easton, Rachael M., Shulman, Gerald I., Previs, Stephen F., Birnbaum, Morris J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796129/
https://ncbi.nlm.nih.gov/pubmed/19883618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.10.004
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