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Symplekin Specifies Mitotic Fidelity by Supporting Microtubule Dynamics
Using a pangenomic loss-of-function screening strategy, we have previously identified 76 potent modulators of paclitaxel responsiveness in non-small-cell lung cancer. The top hit isolated from this screen, symplekin, is a well-established component of the mRNA polyadenylation machinery. Here, we per...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2953045/ https://ncbi.nlm.nih.gov/pubmed/20823274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00758-10 |
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