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Tumor antigen ACRBP normalizes mitotic spindle function to promote cancer cell proliferation

Cancer cells manage to divide in the context of gross chromosomal abnormalities. These abnormalities can promote bypass of normal restraints on cell proliferation, but at a cost of mitotic vulnerabilities that can be attacked by chemotherapy. Determining how cancer cells balance these issues may per...

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Detalhes bibliográficos
Main Authors: Whitehurst, Angelique W., Xie, Yang, Purinton, Scott C., Cappell, Kathryn M., Swanik, Jackie T., Larson, Brittany, Girard, Luc, Schorge, John O., White, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948627/
https://ncbi.nlm.nih.gov/pubmed/20876808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0840
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