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Automated mitotic spindle tracking suggests a link between spindle dynamics, spindle orientation, and anaphase onset in epithelial cells

Proper spindle positioning at anaphase onset is essential for normal tissue organization and function. Here we develop automated spindle-tracking software and apply it to characterize mitotic spindle dynamics in the Xenopus laevis embryonic epithelium. We find that metaphase spindles first undergo a...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Larson, Matthew E., Bement, William M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349782/
https://ncbi.nlm.nih.gov/pubmed/28100633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-06-0355
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