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Muscle Atrophy and Motor Neuron Degeneration in Human NEDL1 Transgenic Mice
Amyotrophic lateral sclerosis (ALS) is the most frequent adult-onset motor neuron disease. Approximately 20% cases of familial ALS show the mutation in the superoxide dismutase-1 (SOD1) gene. We previously demonstrated that homologue to E6AP carboxyl terminus- (HECT-) type ubiquitin protein E3 ligas...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Hindawi Publishing Corporation
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2952905/ https://ncbi.nlm.nih.gov/pubmed/20976258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/831092 |
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