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A Simple PCR Method for Rapid Genotype Analysis of the TH-MYCN Transgenic Mouse

BACKGROUND: The TH-MYCN transgenic mouse is the most widely used murine model of human neuroblastoma, in which a human MYCN oncogene is targeted to neuroectodermal cells of developing mice under the influence of the rat tyrosine hydroxylase promoter. So far, homozygous transgenic mice have been iden...

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Autores principales: Haraguchi, Seiki, Nakagawara, Akira
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731925/
https://ncbi.nlm.nih.gov/pubmed/19730731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006902
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