MapSplice: Accurate mapping of RNA-seq reads for splice junction discovery

The accurate mapping of reads that span splice junctions is a critical component of all analytic techniques that work with RNA-seq data. We introduce a second generation splice detection algorithm, MapSplice, whose focus is high sensitivity and specificity in the detection of splices as well as CPU...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Kai, Singh, Darshan, Zeng, Zheng, Coleman, Stephen J., Huang, Yan, Savich, Gleb L., He, Xiaping, Mieczkowski, Piotr, Grimm, Sara A., Perou, Charles M., MacLeod, James N., Chiang, Derek Y., Prins, Jan F., Liu, Jinze
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2010
Ämnen:
Methods Online
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952873/
https://ncbi.nlm.nih.gov/pubmed/20802226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq622
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