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iMapSplice: Alleviating reference bias through personalized RNA-seq alignment
Genomic variants in both coding and non-coding sequences can have functionally important and sometimes deleterious effects on exon splicing of gene transcripts. For transcriptome profiling using RNA-seq, the accurate alignment of reads across exon junctions is a critical step. Existing algorithms th...
שמור ב:
| הוצא לאור ב: | PLoS One |
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| Main Authors: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6086400/ https://ncbi.nlm.nih.gov/pubmed/30096157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201554 |
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