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iMapSplice: Alleviating reference bias through personalized RNA-seq alignment

Genomic variants in both coding and non-coding sequences can have functionally important and sometimes deleterious effects on exon splicing of gene transcripts. For transcriptome profiling using RNA-seq, the accurate alignment of reads across exon junctions is a critical step. Existing algorithms th...

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書目詳細資料
發表在:PLoS One
Main Authors: Liu, Xinan, MacLeod, James N., Liu, Jinze
格式: Artigo
語言:Inglês
出版: Public Library of Science 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086400/
https://ncbi.nlm.nih.gov/pubmed/30096157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201554
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