MapSplice: Accurate mapping of RNA-seq reads for splice junction discovery

The accurate mapping of reads that span splice junctions is a critical component of all analytic techniques that work with RNA-seq data. We introduce a second generation splice detection algorithm, MapSplice, whose focus is high sensitivity and specificity in the detection of splices as well as CPU...

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Detalhes bibliográficos
Main Authors: Wang, Kai, Singh, Darshan, Zeng, Zheng, Coleman, Stephen J., Huang, Yan, Savich, Gleb L., He, Xiaping, Mieczkowski, Piotr, Grimm, Sara A., Perou, Charles M., MacLeod, James N., Chiang, Derek Y., Prins, Jan F., Liu, Jinze
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952873/
https://ncbi.nlm.nih.gov/pubmed/20802226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq622
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