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One-Pot Etherification of Purine Nucleosides and Pyrimidines

[Image: see text] A one-pot synthesis of ethers derived from inosine, guanosine, 2′-deoxyguanosine, and pyrimidinones is described. Exposure of the heterocycle to 1H-benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and Cs(2)CO(3) produces a reactive intermediate, which i...

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Main Authors: Kokatla, Hari Prasad, Lakshman, Mahesh K.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952719/
https://ncbi.nlm.nih.gov/pubmed/20845979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol101655h
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