MTHFR polymorphisms in relation to ovarian cancer risk

OBJECTIVE: Folate has been hypothesized to influence carcinogenesis due to its dual role in DNA methylation, which regulates gene expression, and synthesis of purine and thymidylate, which is vital for DNA repair. Thus, we examined ovarian cancer risk in relation to two functional polymorphisms (C67...

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Hlavní autoři: Terry, Kathryn L., Tworoger, Shelley S., Goode, Ellen L., Gates, Margaret A., Titus-Ernstoff, Linda, Kelemen, Linda E., Sellers, Thomas A., Hankinson, Susan E., Cramer, Daniel W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952716/
https://ncbi.nlm.nih.gov/pubmed/20817226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2010.08.007
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