MTHFR polymorphisms in relation to ovarian cancer risk

OBJECTIVE: Folate has been hypothesized to influence carcinogenesis due to its dual role in DNA methylation, which regulates gene expression, and synthesis of purine and thymidylate, which is vital for DNA repair. Thus, we examined ovarian cancer risk in relation to two functional polymorphisms (C67...

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Main Authors: Terry, Kathryn L., Tworoger, Shelley S., Goode, Ellen L., Gates, Margaret A., Titus-Ernstoff, Linda, Kelemen, Linda E., Sellers, Thomas A., Hankinson, Susan E., Cramer, Daniel W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952716/
https://ncbi.nlm.nih.gov/pubmed/20817226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2010.08.007
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