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Common genetic variation in IGF1, IGFBP1 and IGFBP3 and ovarian cancer risk
Insulin-like growth factor (IGF) 1 and its binding proteins foster cellular proliferation and inhibit apoptosis. In vitro studies show that IGF1 increases ovarian cell growth and invasive potential, suggesting a role for the IGF1 pathway in ovarian cancer etiology. We evaluated genetic variation in...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2792318/ https://ncbi.nlm.nih.gov/pubmed/19858071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp257 |
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