Common genetic variation in IGF1, IGFBP1 and IGFBP3 and ovarian cancer risk

Insulin-like growth factor (IGF) 1 and its binding proteins foster cellular proliferation and inhibit apoptosis. In vitro studies show that IGF1 increases ovarian cell growth and invasive potential, suggesting a role for the IGF1 pathway in ovarian cancer etiology. We evaluated genetic variation in...

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Autori principali: Terry, Kathryn L., Tworoger, Shelley S., Gates, Margaret A., Cramer, Daniel W., Hankinson, Susan E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2009
Soggetti:
Molecular Epidemiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792318/
https://ncbi.nlm.nih.gov/pubmed/19858071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp257
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