A comprehensive analysis of common IGF1, IGFBP1 and IGFBP3 genetic variation with prospective IGF-I and IGFBP-3 blood levels and prostate cancer risk among Caucasians(†)

The insulin-like growth factor (IGF) pathway has been implicated in prostate development and carcinogenesis. We conducted a comprehensive analysis, utilizing a resequencing and tagging single-nucleotide polymorphism (SNP) approach, between common genetic variation in the IGF1, IGF binding protein (B...

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Autori principali: Schumacher, Fredrick R., Cheng, Iona, Freedman, Matthew L., Mucci, Lorelei, Allen, Naomi E., Pollak, Michael N., Hayes, Richard B., Stram, Daniel O., Canzian, Federico, Henderson, Brian E., Hunter, David J., Virtamo, Jarmo, Manjer, Jonas, Gaziano, J. Michael, Kolonel, Laurence N., Tjønneland, Anne, Albanes, Demetrius, Calle, Eugenia E., Giovannucci, Edward, Crawford, E. David, Haiman, Christopher A., Kraft, Peter, Willett, Walter C., Thun, Michael J., Le Marchand, Loïc, Kaaks, Rudolf, Feigelson, Heather Spencer, Bueno-de-Mesquita, H. Bas, Palli, Domenico, Riboli, Elio, Lund, Eiliv, Amiano, Pilar, Andriole, Gerald, Dunning, Alison M., Trichopoulos, Dimitrios, Stampfer, Meir J., Key, Timothy J., Ma, Jing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
Soggetti:
Association Studies Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901143/
https://ncbi.nlm.nih.gov/pubmed/20484221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq210
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