IGF-1, IGFBP-1, and IGFBP-3 Polymorphisms Predict Circulating IGF Levels but Not Breast Cancer Risk: Findings from the Breast and Prostate Cancer Cohort Consortium (BPC3)

IGF-1 has been shown to promote proliferation of normal epithelial breast cells, and the IGF pathway has also been linked to mammary carcinogenesis in animal models. We comprehensively examined the association between common genetic variation in the IGF1, IGFBP1, and IGFBP3 genes in relation to circ...

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Autores principales: Patel, Alpa V., Cheng, Iona, Canzian, Federico, Le Marchand, Loïc, Thun, Michael J., Berg, Christine D., Buring, Julie, Calle, Eugenia E., Chanock, Stephen, Clavel-Chapelon, Francoise, Cox, David G., Dorronsoro, Miren, Dossus, Laure, Haiman, Christopher A., Hankinson, Susan E., Henderson, Brian E., Hoover, Robert, Hunter, David J., Kaaks, Rudolf, Kolonel, Laurence N., Kraft, Peter, Linseisen, Jakob, Lund, Eiliv, Manjer, Jonas, McCarty, Catherine, Peeters, Petra H. M., Pike, Malcolm C., Pollak, Michael, Riboli, Elio, Stram, Daniel O., Tjonneland, Anne, Travis, Ruth C., Trichopoulos, Dimitrios, Tumino, Rosario, Yeager, Meredith, Ziegler, Regina G., Feigelson, Heather Spencer
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2008
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440354/
https://ncbi.nlm.nih.gov/pubmed/18596909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002578
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