Gene Expression Profiling of U12-Type Spliceosome Mutant Drosophila Reveals Widespread Changes in Metabolic Pathways

BACKGROUND: The U12-type spliceosome is responsible for the removal of a subset of introns from eukaryotic mRNAs. U12-type introns are spliced less efficiently than normal U2-type introns, which suggests a rate-limiting role in gene expression. The Drosophila genome contains about 20 U12-type intron...

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Detalhes bibliográficos
Main Authors: Pessa, Heli K. J., Greco, Dario, Kvist, Jouni, Wahlström, Gudrun, Heino, Tapio I., Auvinen, Petri, Frilander, Mikko J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952598/
https://ncbi.nlm.nih.gov/pubmed/20949011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013215
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