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Discovery of a Novel and Rich Source of Gluten-Degrading Microbial Enzymes in the Oral Cavity

BACKGROUND: Celiac disease is a T cell mediated-inflammatory enteropathy caused by the ingestion of gluten in genetically predisposed individuals carrying HLA-DQ2 or HLA-DQ8. The immunogenic gliadin epitopes, containing multiple glutamine and proline residues, are largely resistant to degradation by...

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Bibliografiska uppgifter
Huvudupphovsmän: Helmerhorst, Eva J., Zamakhchari, Maram, Schuppan, Detlef, Oppenheim, Frank G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952584/
https://ncbi.nlm.nih.gov/pubmed/20948997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013264
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