Unlike thyrotropin, thyroid-stimulating antibodies do not activate phospholipase C in human thyroid slices.

The effects of thyroid-stimulating antibodies (TSAb) and of thyrotropin (TSH) were compared, on the generation of cyclic AMP and inositol phosphates (InsP), in human thyroid slices incubated in vitro, and on the Rapoport cyclic AMP bioassay. The TSAb positive sera were obtained from 19 patients with...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Laurent, E, Van Sande, J, Ludgate, M, Corvilain, B, Rocmans, P, Dumont, J E, Mockel, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295251/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1673689/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115178
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