Unlike thyrotropin, thyroid-stimulating antibodies do not activate phospholipase C in human thyroid slices.

The effects of thyroid-stimulating antibodies (TSAb) and of thyrotropin (TSH) were compared, on the generation of cyclic AMP and inositol phosphates (InsP), in human thyroid slices incubated in vitro, and on the Rapoport cyclic AMP bioassay. The TSAb positive sera were obtained from 19 patients with...

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Pubblicato in:	J Clin Invest
Autori principali:	Laurent, E, Van Sande, J, Ludgate, M, Corvilain, B, Rocmans, P, Dumont, J E, Mockel, J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295251/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1673689/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115178
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