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Cancer metabolism: Is glutamine sweeter than glucose?

Glutamine is an essential nutrient for cancer cells. In this issue of Cancer Cell, Wang et al. show that malignant transformation by Rho GTPases leads to activation of glutaminase, which converts glutamine to glutamate to fuel cancer cell metabolism. Inhibition of glutaminase by a small compound eff...

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Bibliografiska uppgifter
Huvudupphovsmän: Lu, Weiqin, Pelicano, Helene, Huang, Peng
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952340/
https://ncbi.nlm.nih.gov/pubmed/20832746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2010.08.017
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