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Cancer metabolism: Is glutamine sweeter than glucose?

Glutamine is an essential nutrient for cancer cells. In this issue of Cancer Cell, Wang et al. show that malignant transformation by Rho GTPases leads to activation of glutaminase, which converts glutamine to glutamate to fuel cancer cell metabolism. Inhibition of glutaminase by a small compound eff...

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Bibliografische gegevens
Hoofdauteurs: Lu, Weiqin, Pelicano, Helene, Huang, Peng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952340/
https://ncbi.nlm.nih.gov/pubmed/20832746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2010.08.017
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