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The development of antibody –based immunotherapy with (EMD-273063) Hu14.18-IL2 in melanoma and neuroblastoma

Patients with high risk melanoma and neuroblastoma frequently recur despite surgical resection and appropriate adjuvant therapies. Immunotherapy with the immunocytokine, hu14.18-IL2, was developed via fusion of two molecules of IL2 to the monoclonal antibody, 14.18, that recognizes GD2, expressed on...

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Bibliografiske detaljer
Main Authors: Yamane, Brett H., Hank, Jacquelyn A., Albertini, Mark R., Sondel, Paul M.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952306/
https://ncbi.nlm.nih.gov/pubmed/19548853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543780903048911
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