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Mapping the Catalytic Cycle of Schistosoma mansoni Thioredoxin Glutathione Reductase by X-ray Crystallography

Schistosomiasis is the second most widespread human parasitic disease. It is principally treated with one drug, praziquantel, that is administered to 100 million people each year; less sensitive strains of schistosomes are emerging. One of the most appealing drug targets against schistosomiasis is t...

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Hlavní autoři: Angelucci, Francesco, Dimastrogiovanni, Daniela, Boumis, Giovanna, Brunori, Maurizio, Miele, Adriana E., Saccoccia, Fulvio, Bellelli, Andrea
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952258/
https://ncbi.nlm.nih.gov/pubmed/20659890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.141960
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