Metabolic Depression and Increased Reactive Oxygen Species Production by Isolated Mitochondria at Moderately Lower Temperatures

Temperature (T) reduction increases lifespan, but the mechanisms are not understood. Because reactive oxygen species (ROS) contribute to aging, we hypothesized that lowering T might decrease mitochondrial ROS production. We measured respiratory response and ROS production in isolated mitochondria at...

Full description

Saved in:
Bibliographic Details
Main Authors: Ali, Sameh S., Marcondes, Maria-Cecilia Garibaldi, Bajova, Hilda, Dugan, Laura L., Conti, Bruno
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Bioenergetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952254/
https://ncbi.nlm.nih.gov/pubmed/20716522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.155432
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items