Ablation of Succinate Production from Glucose Metabolism in the Procyclic Trypanosomes Induces Metabolic Switches to the Glycerol 3-Phosphate/Dihydroxyacetone Phosphate Shuttle and to Proline Metabolism

Trypanosoma brucei is a parasitic protist that undergoes a complex life cycle during transmission from its mammalian host (bloodstream forms) to the midgut of its insect vector (procyclic form). In both parasitic forms, most glycolytic steps take place within specialized peroxisomes, called glycosom...

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Hlavní autoři: Ebikeme, Charles, Hubert, Jane, Biran, Marc, Gouspillou, Gilles, Morand, Pauline, Plazolles, Nicolas, Guegan, Fabien, Diolez, Philippe, Franconi, Jean-Michel, Portais, Jean-Charles, Bringaud, Frédéric
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952232/
https://ncbi.nlm.nih.gov/pubmed/20702405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.124917
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