Anionic Phospholipid Interactions of the Prion Protein N Terminus Are Minimally Perturbing and Not Driven Solely by the Octapeptide Repeat Domain

Although the N terminus of the prion protein (PrP(C)) has been shown to directly associate with lipid membranes, the precise determinants, biophysical basis, and functional implications of such binding, particularly in relation to endogenously occurring fragments, are unresolved. To better understan...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Boland, Martin P., Hatty, Claire R., Separovic, Frances, Hill, Andrew F., Tew, Deborah J., Barnham, Kevin J., Haigh, Cathryn L., James, Michael, Masters, Colin L., Collins, Steven J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Molecular Biophysics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952229/
https://ncbi.nlm.nih.gov/pubmed/20679345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.123398
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars