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CXCR2 is required for neutrophilic airways inflammation and hyperresponsiveness in a mouse model of human rhinovirus infection

Human rhinovirus (RV) infection is responsible for the majority of virus-induced asthma exacerbations. Using a mouse model of human RV infection, we sought to determine the requirement of CXCR2, the receptor for ELR-positive CXC chemokines, for RV-induced airway neutrophilia and hyperresponsiveness....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nagarkar, Deepti R., Wang, Qiong, Shim, Jee, Zhao, Ying, Tsai, Wan C., Lukacs, Nicholas W., Sajjan, Uma, Hershenson, Marc B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952174/
https://ncbi.nlm.nih.gov/pubmed/19864593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900298
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